The X Factor: Skewing X Inactivation towards Cancer
نویسندگان
چکیده
Increased expression of the epidermal growth factor receptor HER-2/ErbB2 is frequently observed in breast cancer and is targeted by the anticancer drug Herceptin. Now, Zuo et al. (2007) reveal that an X-linked gene encoding the transcription factor FOXP3 is a breast cancer tumor suppressor that represses expression of HER2/ErbB2.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 129 شماره
صفحات -
تاریخ انتشار 2007